Healing has to be interrupted till these consequnces have disappeared, after which treatment has to be followed at a lower dose.
Hoarseness of the voice may be the first symptom of vocal change which can lead to irreversible lowering of the voice. In case signs of virilisation advance, particularly lowering of the voice, treatment must be stopped unless the consequnces are desired management outcomes.
The following negative effects have also been known:
– disorders of liver function
– weight put (in female-to-male transsexuals)
Provion being reduced SAA can not be aromatization also been shown to block aromatase, thus reducing the effects caused by an excess of estrogen produced in the aromatization process (edema, gynecomastia). The use of this drug also helps to build a better quality weight (limit growth of fat tissue for estrogen matter limitations). There is speculation that proviron can lower estrogen receptor, which makes it even more effective in combating the effects caused by the estrogens. The anti-estrogenic properties of Proviron are not unique. Several other steroids also demonstrated similar activity. For example, DHT and Masteron (2methyl-dihydrotestosterone) were successfully used as therapies for gynecomastia and breast cancer due precisely with its anti-estrogenic effect. Prowiron also has a weak ability to inhibit the 5 alpha reductase.
The decline in both female and male libido can be linked to the decline in secretion of HGH in the body. Sexual potency and HGH levels are high in puberty, however diminishes throughout as you percent of men have erection problems as they approach 80 years. A clinical study in South Africa conducted of about 300 ageing adults proved that HGH treatment boosted sexual potency in about 75 percent of men. Furthermore, interviews conducted on people in Denmark using HGH therapy to slow down aging process indicate both men & women experienced improvement in sexual function and libido.